Rheological and textural properties of hydrogels, containing sulfur as a model drug,
made using different polymers types (in English)
Polimery 2019, No 3, 208
The preparation technology and the optimal composition of hydrogels with sulfur prepared using various types of polymers – hydroxyethyl cellulose (HEC), Carbopol 980, and sodium alginate – have been developed. Designed hydrogels were evaluated microscopically, for pH, viscosity and mechanical parameters. In addition, ex vivo bioadhesive properties of obtained hydrogels with hairless mice skin model as adhesive layer were estimated. Hydrogels with sulfur based on sodium alginate possessed the most favorable application properties and were stable at different temperature and humidity conditions during 90 days of storage.